Laying the groundwork of an in vivo macromolecular crystallography platform at Synchrotron SOLEIL

Abstract The identification of protein crystals naturally occurring inside cells and organisms has opened a window for new type macromolecular crystallography (MX) structural biology, referred to as in vivo MX. In the past decade, there have been efforts obtain deeper insights into yet uncontrollable events dictating crystal growth, by further developing sample handling delivery procedures applying these techniques structure determination analysis readily available iv MX systems. To facilitate use larger community, milestones implementation complete pipeline set at Synchrotron SOLEIL (France).